Concepedia

Publication | Closed Access

Antifibrotic effects of interleukin-10 on experimental hepatic fibrosis.

65

Citations

0

References

2008

Year

Lijuan Zhang, Weida Zheng, Yunxin Chen, Yuehong Huang, Zhixin Chen, Shengjun Zhang, Meina Shi, Xiaozhong Wang
PubMed

Abstract

The expression of TGF-beta1, MMP-2 and TIMP-1 increased in liver or in HSC of hepatic fibrosis rats and decreased after treatment with IL-10. The IL-10 could inhibit the activation of HSCs and make an antifibrogenic process come into effect in this way.