Concepedia

Direct real-time PCR-based detection of<i>Neisseria gonorrhoeae</i>23S rRNA mutations associated with azithromycin resistance

Ella Trembizki, Cameron Buckley, Basil Donovan, Marcus Y. Chen, Rebecca Guy, John Kaldor, Monica M Lahra, David G. Regan, Helen Smith, James Ward,

Journal of Antimicrobial Chemotherapy · 2015 · 34 citations · 16 references

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Abstract

Real-time PCR detection of gonococcal 23S rRNA mutations directly from clinical samples is feasible and may enhance culture- and non-culture-based N. gonorrhoeae resistance surveillance.

References

16

Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone

Makoto Ohnishi, Daniel Golparian, Ken Shimuta et al. · Antimicrobial Agents and Chemotherapy · 2011 · 677 citations · Full text

High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel<i>penA</i>Mosaic Allele in a Successful International Clone Causes Treatment Failure

Magnus Unemo, Daniel Golparian, Robert A. Nicholas et al. · Antimicrobial Agents and Chemotherapy · 2011 · 631 citations

Update to the CDC's Sexually Transmitted Diseases Treatment Guidelines, 2010: Oral Cephalosporins No Longer a Recommended Treatment for Gonococcal Infections

Annals of Emergency Medicine · 2012 · 257 citations · Full text

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High-Level Azithromycin Resistance Occurs in <i>Neisseria gonorrhoeae</i> as a Result of a Single Point Mutation in the 23S rRNA Genes

Stephanie Chisholm, J. Dave, C A Ison · Antimicrobial Agents and Chemotherapy · 2010 · 194 citations · Full text

, , +19

Mutation in 23S rRNA Associated with Macrolide Resistance in <i>Neisseria gonorrhoeae</i>

Lai-King Ng, Irene Martín, Gary Liu et al. · Antimicrobial Agents and Chemotherapy · 2002 · 169 citations · Full text