Concepedia

A Coculture Model Mimicking the Intestinal Mucosa Reveals a Regulatory Role for Myofibroblasts in Immune-Mediated Barrier Disruption

Linette E. M. Willemsen, Chantal Schreurs, Hilde Kroes, Ernst Jan Spillenaar Bilgen, Sander J. H. van Deventer, Eric A.F. van Tol

Digestive Diseases and Sciences · 2002 · 14 citations · 33 references

DOI

Concepts

References

33

Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

J L Madara, J Stafford · Journal of Clinical Investigation · 1989 · 761 citations · Full text

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Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases.

R B Sartor · PubMed · 1997 · 396 citations

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Powell, D. W. et al. Myofibroblasts. I. Paracrine cells important in health and disease. Am. J. Physiol. 277, C1-C9

Don W. Powell, Randy C. Mifflin, J. D. Valentich et al. · 1999 · 358 citations

, , +10

Interferon-γ decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin

Adel Youakim, Minoo Ahdieh · American Journal of Physiology-Gastrointestinal and Liver Physiology · 1999 · 283 citations

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IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding

Reid B. Adams, Sarah M. Planchon, James K. Roche · The Journal of Immunology · 1993 · 241 citations

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