Inhibition of glycosidases by aldonolactones of corresponding configuration. 2. Inhibitors of β-<i>N</i>-acetylglucosaminidase

Abstract

Conchie & Levvy (1957) found that, in general, the enzymic hydrolysis of a simple glycoside was in- hibited by the aldonolactone corresponding in configuration to the sugar residue of the substrate. This suggested that the structural requirements necessary for a specific inhibitor of fl-N-acetyl-