Hemodynamic versus hydrodynamic effects of Guglielmi detachable coils on intra-aneurysmal pressure and flow at varying pulse rate and systemic pressure.

Abstract

GDCs significantly reduced flow even in the absence of thrombus, indicating that they have a purely hydrodynamic effect. In the silicone model, the decrease in intra-aneurysmal flow after coiling relied upon the pulse rate in a manner suggesting the presence of resonance phenomena.