The treatment of bacterial endocarditis with penicillin.

Abstract

A LTHOUGH the efficacy of penicillin in the treatment of some bacterial infections is well established, its effect in bacterial endocarditis has been more difficult to evaluate. Herewith are presented the results in twenty-eight patients with streptococcal and staphylococcal endocarditis treated with penicillin* in the three-year period from December, 1942, to December, 1945. This report represents a continuation of the cooperative clinical study of the therapeutic effect of penicillin in bacterial infections and includes further observations of three patients previously rep0rted.l