CRST syndrome and nodular transformation of the liver. A case report.

Abstract

A 56-year-old woman with the CRST syndrome (calcinosis cutis, Raynaud's phenomenon, sclerodactyly, and telangiectasia) associated with nodular transformation of the liver is presented. The sclerodermatous changes involved the entire gastrointestinal tract resulting in dysphagia, steatorrhea, and severe recurrent gastrointestinal bleeding. Some clinical aspects of the affected gastrointestinal tract and the relationship between the CRST syndrome and liver disease are discussed.