PubMed · 1965 · 23 citations · 0 references
MedicineOncologyPharmacologyCancer ImmunologyChemotherapyHypersensitivityDelayed-type HypersensitivityPharmacodynamics Of ImmunotherapiesCutaneous Immune ResponseDelayed Cutaneous HypersensitivityDelayed Drug HypersensitivityDelayed Hypersensitivity ReactionsDrug-induced Delayed HypersensitivityHypersensitivity Reactions To ChemotherapyOral Fluoropyrimidines
Summary The ability to express delayed cutaneous hypersensitivity was assessed in 51 patients with carcinoma. Evidence is presented that 5-fluorouracil and 5-fluoro-2′-deoxyuridine paradoxically potentiate this parameter of immune responsiveness.