ABNORMAL RAPID RHYTHMS ASSOCIATED WITH DIGITOXIN THERAPY

Abstract

Article1 November 1948ABNORMAL RAPID RHYTHMS ASSOCIATED WITH DIGITOXIN THERAPYHAROLD D. LEVINE, M.D., F.A.C.P.HAROLD D. LEVINE, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-5-822 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSeven patients developed abnormal rapid cardiac rhythms (idio-ventricular rhythms, paroxysmal ventricular tachycardia or interference and dissociation) during a recent fifteen and one-half month experience with digitoxin at the Peter Bent Brigham Hospital. Because they seemed more frequent and insidious than with digitalis leaf the incidence and manner of these toxic reactions were studied in this group and in a comparable group which had received digitalis leaf.From February 1, 1943 through May 31, 1945 inclusive, 5,082 patients were treated in the Medical Service. Of this group, 940 (or 18.5 per cent) had heart disease. 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HAGI-PARASCHIVRUSS AL: Deux cas d'intoxication par doses massives de digitaline, Bull. et mém. Soc. méd. des hôp. de Bucarest, 1926, viii, 266. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication December 6, 1947.From the Medical Clinic of the Peter Bent Brigham Hospital, and the Department of Medicine of the Harvard Medical School. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInfluence of exercise on arrhythmias induced by digitalis-diuretic therapy in patients with atrial fibrillationDeliberate Digitalis Intoxication A Comparison of the Toxic Effects of Four Glycoside PreparationsG. CHURCH, M.B., F.R.F.P.S., L. SCHAMROTH, M.B., M.R.C.P., NEIL L. SCHWARTZ, M.B., M.R.C.P., HENRY J. L. 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