Gain‐of‐Function <i>KCNH2</i> Mutations in Patients with Brugada Syndrome - Concepedia

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Gain‐of‐Function <i>KCNH2</i> Mutations in Patients with Brugada Syndrome

43

Citations

17

References

2014

Year

Qi Wang, Seiko Ohno, Wei-Guang Ding, Megumi Fukuyama, Akashi Miyamoto, Hideki Itoh, Takeru Makiyama, Jie Wu, Jiayu Bai, Kanae Hasegawa,

Journal of Cardiovascular Electrophysiology

Abstract

All KCNH2 mutations that we identified in probands with BrS exerted gain-of-function effects on I(Kr) channels, which may partially explain the ECG findings in our patients.

References

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