Effects of chronic sympatho‐inhibition on reflex control of renal blood flow and plasma renin activity in renovascular hypertension

Abstract

Our observations suggest that chronic sympatho-inhibition is an effective antihypertensive therapy in renovascular hypertension. It normalizes MAP and reduces basal PRA without compromising blood flow in the stenosed kidney or altering responses of MAP, haemodynamics and PRA to acute hypotension and stress.