Adverse radiation effect after stereotactic radiosurgery for brain metastases: incidence, time course, and risk factors

Abstract

Although incidence of ARE after SRS was low overall, risk increased rapidly with size and volume, leveling off at a 1-year cumulative incidence of 13%-14%. This study describes the time course of ARE and provides risk estimates by various lesion characteristics and treatment parameters to aid in decision-making and patient counseling.