Surface Functionalization by Plasma Treatment and Click Chemistry of a New Family of Fluorinated Polymeric Materials for Microfluidic Chips

Abstract

The surface modification of a new family of microfluidic chip materials based on a commercial fluorinated thermoplastic polymer (Dyneon THV) was performed for the first time. This modification was done following a four steps approach, involving first the cleaning of surface and then the bromination of the surface by plasma treatment, followed by two successive chemical reactions involving click reaction to graft chemical functions at the polymer surface. It was demonstrated by a thorough surface analysis of Dyneon (XPS, FTIR‐ATR) that surface oxidation allowed increasing the hydrophilicity of the THV surface and brominated film deposition by plasma treatment allowed incorporation of different functional groups on the Dyneon surface through click chemistry.