Intravenous administration of tranexamic acid effectively reduces blood loss in primary total knee arthroplasty in a 610‐patient consecutive case series

Abstract

This study demonstrates a significant benefit from the routine use of TXA for total knee arthroplasty and is one of the first studies to demonstrate a small but significant benefit for IV administration in comparison to intraarticular administration. The routine use of TXA as a central element of a PBMP provides a cost savings and can help reduce the rate of transfusions for total knee arthroplasty.