GENETIC RECOMBINATION BETWEEN HOST-RANGE AND PLAQUE-TYPE MUTANTS OF BACTERIOPHAGE IN SINGLE BACTERIAL CELLS

Abstract

E HAVE previously shown that any two of several independently w arising plaque-type (r) mutants of the bacterial virus TZH interact with each other, in bacterial cells infected with both, to give rise to wild type and double mutant genetic recombinants (HERSHEY and ROTMAN 1948). I n this paper we describe comparable interactions between host-range and r mutants of the same virus. The experiments furnish new information because it has proved possible to count the numbers of all four types of virus found in yields from the mixedly infected bacteria.