RHBMP-2 RELEASE FROM INJECTABLE POLY(DL-LACTIC-CO-GLYCOLIC ACID)/CALCIUM-PHOSPHATE CEMENT COMPOSITES

Abstract

These results indicate that preparation of a PLGA/calcium-phosphate cement composite for the delivery of rhBMP-2 is feasible and that the release of rhBMP-2 is dependent on the composite composition and nanostructure as well as the pH of the release medium.