Concepedia

Acyloxymethyl as a Drug Protecting Group: Part 4. The Hydrolysis of Tertiary Amidomethyl Ester Prodrugs of Carboxylic Acid Agents

Jim Iley, Rui Moreira, Teresa Calheiros, Eduarda Mendes

Pharmaceutical Research · 1997 · 33 citations · 12 references

DOI

Concepts

References

12

Advanced organic chemistry

David Runciman Boyd · Endeavour · 1993 · 1.9K citations

Glycolamide Esters as Biolabile Prodrugs of Carboxylic Acid Agents: Synthesis, Stability, Bioconversion, and Physicochemical Properties

Niels Mørk Nielsenw · Journal of Pharmaceutical Sciences · 1988 · 74 citations

, , +12

Timolol prodrugs: synthesis, stability and lipophilicity of various alkyl, cycloalkyl and aromatic esters of timolol

Anders Buur, Chang Shih-Chieh, Vincent H.L. Lee · International Journal of Pharmaceutics · 1988 · 45 citations

, , +12

Prodrugs of Peptides. 11. Chemical and Enzymatic Hydrolysis Kinetics of N-Acyloxymethyl Derivatives of a Peptide-like Bond

Gitte Juel Rasmussen · Pharmaceutical Research · 1991 · 37 citations

, , +16

Bioreversible carriers in drug design: Theory and application

Kinam Park · Journal of Controlled Release · 1988 · 31 citations

, , +14