Anaesthesia and Intensive Care · 1999 · 107 citations · 21 references
Life SciencesInfectious DiseasesMicrobiologyDiagnostic MicrobiologyMedical MicrobiologySepsisBloodstream InfectionsClinical BacteriologyDiagnostic BacteriologyInfection ManagementNosocomial InfectionsCatheter Site AssessmentCentral Line-associated Bloodstream InfectionsInfection Risk FactorsIntensive Care ComplicationsIntensive Care UseJugular VeinsNeurosurgical Intensive Care Unit ManagementRisk Factors For Bloodstream Infection
This study investigated the incidence of and risk factors for central venous catheter (CVC) infection in intensive care. CVCs were prospectively studied in patients who had lines inserted in general or neurosurgical intensive care and were expected to have the line in situ for at least 72 hours. Catheters (n = 119) were cultured for CVC-related infection (CRI; > 15 colony forming units) and blood cultures done when indicated. CRI was identified in 32 (26.9%) catheters, CVC related bacteraemia in five cases (4.2%) and CVC related sepsis in none. After adjustment for duration of catheterization, independent predictors of CVC related infection were catheter insertion site, with jugular sites having the highest risk, and primary diagnosis, with neurosurgical patients at least risk.
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