Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β‐cells - Concepedia

Concepedia

Publication | Open Access

Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β‐cells

DOI Full Paper Access

33

Citations

32

References

2015

Year

Hiroki Sato, Kazuaki Nagashima, Masahito Ogura, Yuichi Sato, Yumiko Tahara, Kasane Ogura, Gen Yamano, Kazu Sugizaki, Naotaka Fujita, Hisato Tatsuoka,

Journal of Diabetes Investigation

Abstract

Src plays an important role in glucose-induced insulin secretion in pancreatic β-cells through maintaining subcellular localization and activity of glucokinase.

References

	Year	Citations
Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation Weiwei Yang, Yan Xia, Haitao Ji, Nature Nuclear Pkm2Transcriptional RegulationSignal TransductionSignaling PathwayCell Regulation	2011	1K
Glucagon-Like Peptide 1 Induces Pancreatic β-Cell Proliferation Via Transactivation of the Epidermal Growth Factor Receptor Jean Buteau, Sylvain Foisy, Érik Joly, Diabetes	2003	400
Direct Effect of Cholesterol on Insulin Secretion Mingming Hao, W. Steven Head, Subhadra C. Gunawardana, Diabetes	2007	319
Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ Culture Yin Liang, Habiba Najafi, Robert M. Smith, Diabetes	1992	164
Mitochondrial AKAP121 Links cAMP and src Signaling to Oxidative Metabolism Alessandra Livigni, Antonella Scorziello, Savina Agnese, Molecular Biology of the Cell Reductive StressRedox SignalingMitophagyOxidative MetabolismSignal Transduction	2005	149
Metformin Regulates Glucose Transporter 4 (GLUT4) Translocation through AMP-activated Protein Kinase (AMPK)-mediated Cbl/CAP Signaling in 3T3-L1 Preadipocyte Cells Jung Ok Lee, Soo Kyung Lee, Ji Hae Kim, Journal of Biological Chemistry	2012	133
Regulation of β cell glucokinase by S-nitrosylation and association with nitric oxide synthase Megan A. Rizzo, David W. Piston The Journal of Cell Biology	2003	123
Regulation of glucokinase in pancreatic islets by prolactin: a mechanism for increasing glucose-stimulated insulin secretion during pregnancy Anthony J. Weinhaus, Laurence E. Stout, Nicholas Bhagroo, Journal of Endocrinology Glucokinase ActivityPrl ReceptorInsulin SignalingGastrointestinal Peptide HormoneMetabolic Syndrome	2007	101
Interaction of 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFK-2/FBPase-2) With Glucokinase Activates Glucose Phosphorylation and Glucose Metabolism in Insulin-Producing Cells Laura Massa, Simone Baltrusch, David A. Okar, Diabetes Metabolic RemodelingInsulin-producing CellsInsulin SignalingMetabolic SyndromeGlucose Metabolism	2004	98
Exendin-4 Suppresses Src Activation and Reactive Oxygen Species Production in Diabetic Goto-Kakizaki Rat Islets in an Epac-Dependent Manner Eri Mukai, Shimpei Fujimoto, Hiroki Sato, Diabetes	2010	91

Page 1