Concepedia

Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β‐cells

Hiroki Sato, Kazuaki Nagashima, Masahito Ogura, Yuichi Sato, Yumiko Tahara, Kasane Ogura, Gen Yamano, Kazu Sugizaki, Naotaka Fujita, Hisato Tatsuoka,

Journal of Diabetes Investigation · 2015 · 33 citations · 32 references

DOIFull text

Open access

Abstract

Src plays an important role in glucose-induced insulin secretion in pancreatic β-cells through maintaining subcellular localization and activity of glucokinase.

References

32

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

Weiwei Yang, Yan Xia, Haitao Ji et al. · Nature · 2011 · 1K citations · Full text

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Glucagon-Like Peptide 1 Induces Pancreatic β-Cell Proliferation Via Transactivation of the Epidermal Growth Factor Receptor

Jean Buteau, Sylvain Foisy, Érik Joly et al. · Diabetes · 2003 · 400 citations

Direct Effect of Cholesterol on Insulin Secretion

Mingming Hao, W. Steven Head, Subhadra C. Gunawardana et al. · Diabetes · 2007 · 319 citations · Full text

Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ Culture

Yin Liang, Habiba Najafi, Robert M. Smith et al. · Diabetes · 1992 · 164 citations

Mitochondrial AKAP121 Links cAMP and src Signaling to Oxidative Metabolism

Alessandra Livigni, Antonella Scorziello, Savina Agnese et al. · Molecular Biology of the Cell · 2005 · 149 citations · Full text

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