Risk of diarrhoea in a long‐term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the <i>UGT1A8*2</i> variant allele

Abstract

These results suggest that a possible inhibition of biliary excretion of MPA metabolites by CsA and a decreased intestinal production of these metabolites in UGT1A8 2 carriers may be protective factors against MMF-induced diarrhoea.