Photoaptamer Technology: Development of Multiplexed Microarray Protein Assays

Abstract

healthy individuals. However, we found that this positivity was dependent on the primer pairs used and that, with careful selection of the primer pair, the presence of mRNA was specific for thyroid cancer and corresponded to the presence of extrathyroidal disease and the presence of Tg mRNA transcripts. With further refinement of this assay and with the development of a quantitative real-time PCR procedure, the measurement of TSHR mRNA by RT-PCR may serve as a specific and sensitive tool for monitoring of thyroid cancer.