Mid-infrared spectroscopy as a polymer selection tool for formulating amorphous solid dispersions

Abstract

Based on the observed ability of mid-IR analysis to enable the characterization of intermolecular polyphenol-polymer interactions and based on the correlation between the extent of intermolecular interactions and the crystallization-inhibiting performance of polymers, it can be concluded that this technique is an important tool for the rational formulation of solid dispersions with optimized physical stability.