Variable hematopoietic responses to acute photons, protons and simulated solar particle event protons.

Abstract

The data demonstrate that exposure to proton radiation mimicking a solar explosion induces abnormalities in leukocytes, erythrocytes and platelets that may have adverse health consequences. However, the damaging effects of sSPE on leukocytes and platelets were generally less pronounced compared to the other radiation regimens. Results obtained with photons (gamma-rays, X-rays) and monoenergetic protons at space-relevant total doses may not necessarily predict biological responses after exposure to a solar particle event.