Association between AMH, oocyte number and availability of embryos for cryopreservation in IVF.

Abstract

AIM: To investigate possible associations between serum anti-Müllerian hormone (AMH) levels, the number of oocytes collected and the availability and suitability of produced embryos for cryopreservation in in-vitro fertilization (IVF) cycles. PATIENTS AND METHODS: Sixty women in their first IVF/intracytoplasmic sperm injection (ICSI) cycle were studied. The short stimulation protocol was used for controlled ovarian hyperstimulation. AMH levels were measured during the menstrual cycle preceding treatment. RESULTS: A strong, positive correlation between AMH and the number of collected oocytes was found. The patients with available and suitable embryos for cryopreservation had significantly higher levels of AMH. CONCLUSION: AMH appears to be a valuable marker mainly for ovarian reserve and response to IVF treatment. AMH levels are strongly associated with the number of retrieved oocytes and the availability of supernumerary embryos suitable for cryopreservation.