Prevalence of migraine in persons with the 3243A&gt;G mutation in mitochondrial <scp>DNA</scp>

Abstract

A high prevalence of migraine in persons with the mDNA 3243A>G mutation was found. This finding suggests a clinical association between a monogenetically inherited disorder of mitochondrial dysfunction and susceptibility to migraine. Mitochondrial DNA aberrations may contribute to the pathogenesis of migraine.