Southern Medical Journal · 1978 · 40 citations · 0 references
Veterinary MedicineInternal MedicinePharmacotherapyGastroenterologyHepatologyInflammationChemical-induced HepatotoxicityGranulomatous InflammationHepatic NecrosisHepatic ToxicityInflammatory Bowel DiseaseLiver DiseaseCrohn Disease-associated GranulomasGranulomatous HepatitisGranulomatous Liver DiseaseHepatic Inflammatory InjuryInflammatory Bowel Disease ImmunopathogenesisInflammatory Bowel Disease Pathology
Granulomatous hepatitis has been associated with many conditions, including chronic ulcerative colitis and sulfonamide therapy. We report a patient with ulcerative colitis in whom hepatic granulomatosis was associated with salicylazosulfapyridine (Azulfidine). Sulfonamides should be considered a possible cause of hepatotoxicity when used therapeutically in inflammatory bowel disease.