Persons with Down syndrome have features of premature aging detectable at routine MR imaging.
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Magnetic Resonance Imaging of Brain Iron
Burton P. Drayer, Peter C. Burger, Robert H. Darwin et al. · Europe PMC (PubMed Central) · 1986 · 174 citations · Full text
LONGEVITY AND MORTALITY IN DOWN'S SYNDROME
Michael E. Thase · Journal of Intellectual Disability Research · 1982 · 154 citations
Down Syndrome, Life Span, Aging +15