L-Arginine Pathway in COPD Patients with Acute Exacerbation: A New Potential Biomarker

Abstract

COPD is associated with elevated L-arginine, ADMA and SDMA serum levels. In patients with AECOPD, production of ADMA and SDMA are more pronounced presumably due to more severe hypoxic insult. Methylated arginine derivatives in the sera may help early recognition of AECOPD.