Intraoperative Anaphylaxis to Latex

Abstract

Since systemic reactions to latex were first described 5 years ago, an increasing number of these type I (IgE-mediated) allergic reactions have been reported in patients with long-term exposure to latex.1-6 The allergic manifestations range from localized erythema, urticaria, and pruritus of the exposed area to life-threatening angioedema and anaphylaxis. The reported cases of anaphylaxis have almost exclusively occurred intraoperatively. The children at greatest risk are those with myelomeningocele or congenital urologic abnormalities.7,8 These children have undergone multiple surgical procedures and/or repeated bladder catheterizations and radiologic procedures in which rubber catheters are used. We describe two patients who experienced intraoperative anaphylaxis to latex.