Journal of Statistical Software · 2006 · 625 citations · 1 references
Life SciencesBioinformaticsGeneticsComputational BiologyGenomic Data AnalysisGenomicsGenetic MappingGenomic Data VisualizationGenotype-phenotype Association AnalysisHeatmap VisualizationLinkage AnalysisLinkage DisequilibriumGenomic HeatmapsHeat Map RepresentationHeat MapsLinkage Disequilibrium AnalysisLinkage Disequilibrium MappingMapping FunctionsPairwise Linkage DisequilibriumSingle-nucleotide Polymorphisms
We describe the R function LDheatmap() which produces a graphical display, as a heat map, of pairwise linkage disequilibrium measurements between single nucleotide polymorphisms within a genomic region. LDheatmap() uses the grid graphics system, an alternative to the traditional R graphics system. The features of the LDheatmap() function and the use of tools from the grid package to modify heat maps are illustrated by examples.
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A haplotype map of the human genome