Enhanced resolution in a multimode fiber imaging system

Abstract

Multimode fibers have recently been demonstrated to be a promising candidate for ultrathin and high resolution endoscopy. However, this method does not offer depth discrimination for fluorescence imaging and the numerical aperture of the fiber limits its resolution. In this paper we demonstrate optical sectioning and enhanced resolution using saturated excitation and temporal modulation. Using a continuous wave laser excitation, we demonstrate improved resolution in all three dimensions and increased image contrast by rejecting out of focus light.