Hypoperfusion in the limbic system and prefrontal cortex in depression: SPECT with anatomic standardization technique.

Abstract

Decreases in CBF in these regions may be related to impaired attention as well as cognitive and emotional responses, which have been recognized as usual symptoms in depression. The anatomic standardization technique promises to be useful for group comparison analysis of brain SPECT on a pixel-by-pixel basis for individual neurological and psychiatric diseases.