Immune‐reactive soluble <scp>OX</scp>40 ligand, soluble <scp>CD</scp>40 ligand, and interleukin‐27 are simultaneously oversecreted in platelet components associated with acute transfusion reactions

Abstract

This study demonstrates the putative participation of PLT-derived sOX40L, IL-27, and sCD40L, which accumulate in PC supernatants, with inflammatory-type ATRs. Further studies are required to determine the clinical significance of these findings to forecast preventive measures whenever possible.