Concepedia

A randomised, double-blind, placebo-controlled multi-centre phase III trial of XELIRI/FOLFIRI plus simvastatin for patients with metastatic colorectal cancer

Seong Hoon Lim, Tae Won Kim, Yuancheng Hong, Seung Woo Han, Kyung‐Ha Lee, Hye Jin Kang, Inwoo Hwang, J Y Lee, Hyo Song Kim, S T Kim,

British Journal of Cancer · 2015 · 86 citations · 23 references

DOIFull text

Open access

Abstract

The addition of 40 mg simvastatin to the XELIRI/FOLFIRI regimens did not improve PFS in patients with previously treated metastatic colorectal cancer nor did it increase toxicity.

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