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First use of GdDTPA/dimeglumine in man.
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1984
Year
UrologyLow ToxicityGd-dtpa ComplexMedicinePhysiologyChronic Kidney DiseaseFirst UseStandardizationRenal PathophysiologyClinical ChemistryPharmacologyDimeglumine SaltKidney ResearchDrug DiscoveryPharmaceutical Research
The dimeglumine salt of the Gd-DTPA complex has a strong paramagnetic effect and a very low toxicity in animals. This report of its use in human volunteers confirms its low toxicity and indicates its usefulness in the enhancement of signal intensity of the kidney and bladder.