Hypoglycemic and antihyperglycemic effects of Anabasis articulata (Forssk) Moq (Chenopodiaceae), an Algerian medicinal plant

Abstract

Anabasis articulata leaves decoction is widely used by Algerian traditional medicine practitioners as a remedy for the treatment of diabetes. The aqueous extract was found to be non-toxic at 1000 mg/kg, as no deaths or hazardous signs were recorded during treatment or the observation period (24 and 72 h) in either control or treated groups of mice. Experiments were performed in non-diabetic mice, and in hyperglycemic mice (glucose treated and alloxan treated mice) to confirm the antidiabetic potential of A. articulata. Our results showed that the orally administration at a dose of 400 mg/kg decreased the glycaemia by 29.89% after 6 h (p confirms the antidiabetic proprieties of A. articulata leaves previously reported by Algerian healers.