Concepedia

Expression of pro‐apoptotic Bax and anti‐apoptotic Bcl‐2 proteins in human retinoblastoma

Lata Singh, Neelam Pushker, Neeru Saini, Seema Sen, Anjana Sharma, Sameer Bakhshi, Bhavna Chawla, Seema Kashyap

Clinical and Experimental Ophthalmology · 2014 · 76 citations · 23 references

DOIFull text

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Abstract

Our findings suggest that these apoptotic regulatory proteins may serve as poor prognostic markers and can be used as a therapeutic target for the treatment of invasive retinoblastoma. Further functional studies are required to explore the role of Bax and Bcl-2 in retinoblastoma.

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