Natural Course of Neuroblastoma Detected by Mass Screening: A 5-Year Prospective Study at a Single Institution

Abstract

None of our patients showed evidence of transition from favorable to unfavorable prognosis, a finding that points to a reduction in the significance of screening as a public health measure. Until results of ongoing screening trials involving older patients have been evaluated, the observation program can be used as a temporary measure to avoid, with little risk, unnecessary surgical intervention.