In Vivo Visualization of Pyloric Mucosal Hypertrophy in Infants with Hypertrophic Pyloric Stenosis

Abstract

Mucosal redundancy is a constant associated finding in IHPS. Although the origin of the redundancy and a cause-and-effect relationship are difficult to establish, our findings support the hypothesis that hypergastrinemia may be implicated in the pathogenesis of IHPS, and suggest that mucosal thickening could be implicated as one of the initiating factors in its development.