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Prothrombin Complex Concentrate Is Effective in Treating the Anticoagulant Effects of Dabigatran in a Porcine Polytrauma Model

DOI

48

Citations

36

References

2015

Year

Markus Honickel, Till Braunschweig, Joanne van Ryn, Hugo Ten Cate, Henri M.H. Spronk, Rolf Rossaint, Oliver Grottke
Anesthesiology

Abstract

Four-factor PCC (50 or 100 U/kg) is effective in reducing blood loss in dabigatran-anticoagulated pigs, but higher doses may induce a procoagulant state.

References

YearCitations

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