<i>Streptococcus pneumoniae</i> worsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ibα

Abstract

S. pneumoniae infection augments atherosclerosis and exacerbates ischemic brain injury via IL-1 and platelet-mediated systemic inflammation. These mechanisms may contribute to diverse cardio- and cerebrovascular pathologies in humans.