Publication | Open Access
Simple Fluorometric Method for Estimating Practolol [1-(4-Aminophenoxy)-3-isopropylaminopropan-2-ol] in Blood and Urine
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1972
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Pharmaceutical ScienceFluorometric MethodPharmacotherapyExperimental PharmacologyPharmaceutical ChemistryExcitation WavelengthWeak AcidMedicinal ChemistryBioanalysisClinical ChemistryChromatographyTherapeutic Drug MonitoringBiochemistryMechanism Of ActionSimple Fluorometric MethodPharmacologyUrologyNatural SciencesMedicinePharmacokineticsDrug DiscoveryDrug Analysis
Abstract A fluorometric method has been devised for determining practolol [1-(4-aminophenoxy)-3-isopropylaminopropan-2-ol], a new beta-adrenergic receptor antagonist, in blood and urine. The conjugate of deacetylated practolol with nitrosonaphthol is highly fluorescent in weak acid. The excitation wavelength used is 460 nm, the emission wavelength 550 nm.