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Proton pump inhibitors drastically modify triosephosphate isomerase from Giardia lamblia at functional and structural levels, providing molecular leads in the design of new antigiardiasic drugs

Giardia LambliaBiochemistryMedicineNatural SciencesTriosephosphate IsomeraseProton Pump InhibitorsMechanism Of ActionPharmacotherapyStructure-function Enzyme KineticsDrug DevelopmentChemical BiologyPharmacologyInhibitory ActivityDrug Discovery