Effect of polymer charge on the formation and stability of anti-inflammatory drug loaded nanostructured lipid carriers: physicochemical approach

Abstract

Proposed model of NSAID-loaded and polymer-coated NLC along with its size dependence (<graphic xmlns:xlink="http://www.w3.org/1999/xlink" id="ugr1" xlink:href="http://pubs.rsc.org/RA/2015/c5ra11066a/c5ra11066a-u1..gif" />), PDI (<graphic xmlns:xlink="http://www.w3.org/1999/xlink" id="ugr2" xlink:href="http://pubs.rsc.org/RA/2015/c5ra11066a/c5ra11066a-u2..gif" />), release rate (<graphic xmlns:xlink="http://www.w3.org/1999/xlink" id="ugr3" xlink:href="http://pubs.rsc.org/RA/2015/c5ra11066a/c5ra11066a-u3..gif" />), and absorption maxima (<graphic xmlns:xlink="http://www.w3.org/1999/xlink" id="ugr4" xlink:href="http://pubs.rsc.org/RA/2015/c5ra11066a/c5ra11066a-u4..gif" />) as well as its morphology and antibacterial activity.