Wound healing anomalies after excimer laser photorefractive keratectomy: correlation of clinical outcomes, corneal topography, and confocal microscopy.

Abstract

Topographic anomalies of wound healing are common after PRK. Vision and predictability are reduced by anomalies 1 month post-PRK but anomalies often resolve by 6 months. Marked improvement of vision occurs even when anomalies persist. Central islands appear to consist of persistent dense subepithelial extracellular deposits. Local scars are caused by new collagen deposition.