Manganese superoxide dismutase <scp>Ile58Thr</scp> , catalase <scp>C</scp> ‐262 <scp>T</scp> and myeloperoxidase <scp>G</scp> ‐463 <scp>A</scp> gene polymorphisms in patients with prostate cancer: relation to advanced and metastatic disease

Abstract

It seems that there is no association of prostate cancer with MnSOD Ile58Thr polymorphism, whereas the TT genotype in the CAT C-262T polymorphism and the GG genotype in the MPO G-463A polymorphism may be associated with increased prostate cancer risk. The TT genotype in the CAT C-262T gene polymorphism may also be a risk factor in tumour progression and metastasis among Turkish men.