Concepedia

Do Stem Cells Play Dice?

Tariq Enver, C M Heyworth, Tim Dexter

Blood · 1998 · 209 citations · 28 references

DOI

Concepts

Abstract

THE DEBATE SURROUNDING the issue of whether or not hematopoietic stem cell commitment and differentiation are orchestrated in a cell-intrinsic or cell-extrinsic fashion is in many ways akin to the nature versus nurture debate that typifies discussions of human personal potentials. We have published

References

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Differentiation and proliferation of hematopoietic stem cells

Megumu Ogawa · Blood · 1993 · 1.4K citations

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Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

Hong Wu, Xin Liu, Rudolf Jaenisch et al. · Cell · 1995 · 1K citations · Full text

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Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization

D Grail, G. S. Hodgson, D Metcalf et al. · Blood · 1994 · 947 citations · Full text

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Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology.

Edouard G. Stanley, Graham J. Lieschke, D Grail et al. · Proceedings of the National Academy of Sciences · 1994 · 884 citations

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Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin

Karen E. Brown, Simon S. Guest, Stephen T. Smale et al. · Cell · 1997 · 798 citations · Full text

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