Second natural history study of congenital heart defects. Results of treatment of patients with aortic valvar stenosis.

Langford Kidd, W. Michael O’Fallon, Daniel R. Pieroni, Robert R. Wolfe, William H. Weidman

PubMed · 1993 · 372 citations · 0 references

Abstract

Patients with gradients < 25 mm Hg can be followed medically; however, progressive stenosis can occur, and approximately 20% will require intervention. If the gradient is > or = 50 mm Hg, there is a risk of serious arrhythmias and, possibly, sudden death. If the gradient is > or = 80 mm Hg, intervention is clearly indicated; as techniques improve, delaying intervention in patients with gradients of 50-79 mm Hg may not be advantageous. Patients with gradients of 25-49 mm Hg can be followed medically with annual evaluation.