Stromelysin-1 (MMP-3) in synovial fluid of patients with rheumatoid arthritis has potential to cleave membrane bound Fas ligand. - Concepedia

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Stromelysin-1 (MMP-3) in synovial fluid of patients with rheumatoid arthritis has potential to cleave membrane bound Fas ligand.

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References

2001

Year

Hiroaki Matsuno, Kazuo Yudoh, Yuko Watanabe, Fujio Nakazawa, Hiromichi Aono, Tomoatsu Kimura

Abstract

There was significant correlation between the concentration of sFasL and MMP-3 in SF of patients with RA. In addition, our data indicate that the shedding of FasL may be regulated by MMP-3 in the joint of patients with RA.