Publication | Closed Access
The Effect of Antilymphocytic Serum on Circulating Antibody Levels
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1951
Year
Laboratory ImmunologyHumoral ResponseImmunologySalmonella Paratyphi BImmunotherapyFlagellar AgglutininInflammationAdrenal GlandHematologySepsisAutoantibodiesLaboratory MedicineSummary AdministrationAutoimmune DiseaseGranulocyteAutoimmunityHumoral ImmunityAntibody ScreeningCirculating Antibody LevelsImmunosuppressionMedicine
Summary Administration of antilymphocytic serum to rats previously immunised with Salmonella paratyphi B failed to produce a rise in flagellar agglutinin titres despite a profound fall in the number of circulating lymphocytes. This fall in lymphocyte count occurred even in adrenalectomised animals, suggesting that it is not dependent on an adrenal mechanism.